Artificial blood vessel: The Holy Grail of peripheral vascular surgery

Pursuing the "Holy Grail".

Over the past decade, several large, randomized trials have allowed us to better define the appropriate population for primary prevention implantable cardioverterdefibrillator (ICD) placement, saving thousands of lives every year. MADIT II (Multicenter Automatic Defibrillator Implantation Trial II) and SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial) have demonstrated a survival benefit o...

The Holy Grail of Psychiatry

"Holy Grail" is a well-known metaphor for the eternal spiritual pursuit for truth and wisdom. It suggests that in order for us to find what no one has found, we must search where few have looked. In 2013, a group led by Helen Mayberg published a groundbreaking paper that sought an answer to one of the most discussed conundrums in psychiatry and neuroscience: Can specific patterns of brain activ...

Spinal anesthesia: the Holy Grail?

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Searching for the Holy Grail?

Disaggregation: The Holy Grail of Energy Efficiency?

This paper aims to address two timely energy problems. First, significant low-cost energy reductions can be made in the residential and commercial sectors, but these savings have not been achievable to date. Second, billions of dollars are being spent to install smart meters, yet the energy saving and financial benefits of this infrastructure – without careful consideration of the human element...